Human myeloma cells express the CD38 ligand CD31
نویسندگان
چکیده
منابع مشابه
CD38 binding to human myeloid cells is mediated by mouse and human CD31.
Soluble forms of membrane receptors are emerging candidates as physiological regulators of leukocyte trafficking. In the present study, we found that the soluble form of the CD38 antigen (sCD38) bears a binding domain of low affinity for a cellular receptor on U937 cells. Cross-linking and peptide-mapping studies confirmed the physical association and the identification of the U937 receptor as ...
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متن کاملHuman CD38 (ADP-ribosyl cyclase) is a counter-receptor of CD31, an Ig superfamily member.
Human CD38 is a cell surface molecule involved in the regulation of lymphocyte adhesion to endothelial cells. This suggests that HUVEC bear a ligand(s) for CD38 on the cell surface. By means of the mAb Moon-1, which specifically inhibits CD38-mediated cell adhesion, we have identified a trans-membrane 130-kDa molecule acting as a ligand for CD38. Here, we report that the molecule recognized by ...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 1999
ISSN: 0007-1048,1365-2141
DOI: 10.1111/j.1365-2141.1999.01321.x